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diagnosis and treatment of infertility, first/second/third generation IVF (including
egg/sperm donation), microsperm retrieval, embryo freezing and resuscitation, artificial
insemination (including husband's sperm and sperm donation), paternity testing, chromosomal
disease
diagnosis, high-throughput gene sequencing, endometrial receptivity gene testing and other
clinical
technology applications. Many of these technologies are at the leading level both domestically
and
internationally.
You who have come here may have been diagnosed with infertility, or you may be wondering if you are also one of the groups that are difficult to conceive.
Infertility is defined as having normal sexual activity under the age of 35 without contraception for more than one year without successful pregnancy, or being over 35 without contraception for more than six months.
There are many reasons for infertility, so each couple will need different artificial reproductive technologies due to different infertility reasons. Artificial reproduction can be roughly divided into two types: artificial insemination and in vitro fertilization
Artificial insemination (IUI), in simple terms, involves directly injecting processed sperm into the uterus to reduce the fatigue of sperm crossing the cervix. What about in vitro fertilization?
In vitro fertilization, also known as in vitro fertilization, is the abbreviation for IVF in medical terms, spelled as In Vitro Fertilization.
The process of in vitro fertilization can be roughly divided into: induction of ovulation → egg retrieval → fertilization and culture → implantation → pregnancy test
Who is suitable for in vitro fertilization? Indications for in vitro fertilization
I would recommend friends who have the following questions to consider IVF in the near future
fallopian tube obstruction
Abnormal ovarian function
Endometriosis
Uterine factors
Sperm problem
unexplained infertility
Artificial insemination treatment has failed more than three times
Female advanced age (over 38 years old)
Regarding IVF technology: ICSI, PGS
Since the birth of the first test tube baby in 1978, the technology of in vitro fertilization has continued to advance and can be roughly divided into three generations:
The first generation of IVF: In vitro fertilization+embryo implantation (IVF-ET), which means taking out the sperm and egg and placing them in the same culture dish, allowing them to freely combine. This can solve female factors and mild male infertility problems.
The first generation of in vitro fertilization has limited assistance for elderly or low sperm quality patients, with a success rate of approximately 20-30%.
Second generation IVF: Single sperm microinjection (ICSI) involves fixing the egg with a microscope arm, and then selecting the best quality sperm. The sperm is injected directly into the cytoplasm of the egg through a needle tube
The second generation of in vitro fertilization can solve male infertility and the problem of difficulty in penetrating the egg shell at an advanced age. The success rate of fertilization is about 70%; The success rate of pregnancy is about 30-40%.
Third generation IVF: Preimplantation Genetic Screening/Diagnosis (PGS/PGD). In clinical practice, many causes of infertility are related to chromosomal genetic abnormalities in embryos.
Therefore, when the fertilization of the sperm and egg is completed and the embryo is cultured to the blastocyst stage on the 5th day, 1/10 of the cells will be taken out for molecular diagnosis to confirm that the embryo has no genetic diseases or errors, and then implanted into the mother's body. This examination is not a necessary item, please reach a consensus with your family and reproductive doctor.
Third generation IVF can assist patients with habitual miscarriage and repeated implantation failures in further investigating the causes. The success rate of normal embryo implantation can be increased to up to 85%.
Despite the rapid development of infertility treatment techniques, the difficulty and solutions of infertility vary among individuals. Therefore, designing personalized treatment content based on the patient's condition is the best approach.
